Grounded in real guidelines, gated for safety, and set up inside Claude in about ten minutes. No coding. You copy an instruction block, paste it into a Claude project, and start.
Do this for the Evidence assistant first — it works right away and touches no patient data. Add the others when you're ready.
Go to claude.ai → Projects → Create project. Name it ONCO-EVIDENCE.
On the Evidence card below, press Copy instructions. In your project, open Set project instructions and paste.
Download the files listed on the card and upload them to Project knowledge. For Evidence this is quick — the safety files and a couple of references.
Ask it for a drug dose. It should refuse and tell you to verify — not answer from memory. If it confidently gives a dose, re-check that HARD_GATES.md uploaded.
Ask a real literature question from your week. When it feels natural, come back and add Teach & Communicate, then the clinical assistants with your pharmacist.
Each assistant is one Claude project. The instruction block is what makes it safe — copy it in full. Build them top to bottom; the order is deliberate.
Search, appraise and synthesise the literature — with every citation verified.
Start here · works right away
The safest place to begin. It touches no patient data and needs almost no setup — paste the instructions and ask it a literature question.
Slide decks, teaching material, and patient letters — bilingual, fact-gated.
Works with light setup
Creative with form, never with fact. Good second project to add once Evidence feels comfortable.
Differential diagnosis, treatment-option maps, MDT prep, follow-up schedules — options, never decisions.
Needs your local knowledge base first
Only build this after the Tier B local files (formulary, capability map) are filled — otherwise it will suggest tests your centre cannot run. Run it in shadow mode for 60 days before it advises anyone.
An independent second check on a chemotherapy prescription: doses, adjustments, interactions, omissions.
Pharmacist sign-off required before clinical use
The highest-stakes assistant. It must not go live until your clinical pharmacist has filled and signed the dose and interaction files, and until it passes all twelve red-team tests. Until then it answers every dose question with “not in my knowledge base” — which is correct, not broken.
These are empty templates on purpose. The doses, interactions and formulary are not filled in — because an assistant that invents them is worse than no assistant at all. You and your clinical pharmacist fill them from NCCN / BNF / your local protocol. Files marked sign-off must be signed before the Rx Cross-Check assistant may be used on a patient.